Drug reference
Fluocinonide
Corticosteroid · Anti-inflammatory (topical)
CorticosteroidAnti-inflammatory (topical)
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
—
not curated
Mechanism
Fluocinonide, a topical corticosteroid, primarily exerts its therapeutic effects through potent anti-inflammatory activity. It inhibits various components of the immune system and the inflammatory response. Additionally, its antimitotic effects on human epidermis contribute to its efficacy in conditions like psoriasis, which are characterized by increased cell turnover.
Indications
Severe inflammatory skin disorders such as eczemas unresponsive to less potent corticosteroidsPsoriasis
Dosing
- Adult
- Apply 1–2 times a day, to be applied thinly
- Pediatric
- Apply 1–2 times a day, to be applied thinly (Licensed for use in children, age range not specified by manufacturer)
Contraindications
- Known infections of some consequence (use only if absolutely necessary and with concomitant antimicrobial or antifungal therapy)
Side effects
Common
Increased risk of infection
Serious
- Cushing’s syndrome
Related guidelines
Other Corticosteroid drugs
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Sources: Katzung, BNF·Verified: 2026-05-10 · House clinical team