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Fluocinonide

Corticosteroid · Anti-inflammatory (topical)

CorticosteroidAnti-inflammatory (topical)
CDSCO approved
EXCRETION
not curated
INTERACTIONS
none in our sources
PREGNANCY
not curated

Mechanism

Fluocinonide, a topical corticosteroid, primarily exerts its therapeutic effects through potent anti-inflammatory activity. It inhibits various components of the immune system and the inflammatory response. Additionally, its antimitotic effects on human epidermis contribute to its efficacy in conditions like psoriasis, which are characterized by increased cell turnover.

Indications

Severe inflammatory skin disorders such as eczemas unresponsive to less potent corticosteroidsPsoriasis

Dosing

Adult
Apply 1–2 times a day, to be applied thinly
Pediatric
Apply 1–2 times a day, to be applied thinly (Licensed for use in children, age range not specified by manufacturer)

Contraindications

  • Known infections of some consequence (use only if absolutely necessary and with concomitant antimicrobial or antifungal therapy)

Side effects

Common
Increased risk of infection
Serious
  • Cushing’s syndrome

Related guidelines

Other Corticosteroid drugs

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Sources: Katzung, BNF·Verified: 2026-05-10 · House clinical team