Drug reference

Fluorometholone

Corticosteroid · Anti-inflammatory

Also known as FML, FML FORTE, Fluorometholone acetate, FLAREX

CorticosteroidAnti-inflammatory

CDSCO approvedSchedule H

EXCRETION

—

not curated

INTERACTIONS

—

none in our sources

PREGNANCY

—

not curated

Mechanism

Glucocorticoids, including fluorometholone, exert their anti-inflammatory effects by binding to intracellular glucocorticoid receptors. This leads to alterations in gene expression, resulting in the inhibition of pro-inflammatory mediators and suppression of immune cell activity, thereby reducing inflammation.

Indications

Local treatment of inflammation (short term) to the eyeallergic conjunctivitisgiant papillary conjunctivitiskeratitisocular burnspostoperative ocular inflammationuveitisvernal keratoconjunctivitis

Dosing

Adult: Apply every 1 hour for 24–48 hours, then reduced to 2–4 times a day to the eye.
Pediatric: Child 2–17 years: Apply every 1 hour for 24–48 hours, then reduced to 2–4 times a day to the eye.

Contraindications

Known active infections (administer only if absolutely necessary and concomitantly with appropriate and effective antimicrobial or antifungal therapy)
Risk of central serous chorioretinopathy