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Ulipristal Acetate

Progestogen · Emergency contraception

Also known as ella, ellaOne

ProgestogenEmergency contraception
CDSCO approvedSchedule H
EXCRETION
not curated
INTERACTIONS
4 major
SEVERE in our sources
PREGNANCY
not curated
Top interactions
  • BerotralstatSevereDatabaseDDInter
  • ColchicineSevereDatabaseDDInter
  • EdoxabanSevereDatabaseDDInter
  • VenetoclaxSevereDatabaseDDInter

Mechanism

Ulipristal acetate acts as a partial agonist at the progesterone receptor. For emergency contraception, its mechanism primarily involves delaying or preventing ovulation, likely through actions on the hypothalamus.

Indications

Emergency contraception

Dosing

Adult
30 mg for 1 dose, to be taken as soon as possible after coitus, but no later than after 120 hours
Max dose
30 mg as a single dose

Side effects

Common
Back painBreast tendernessDizzinessFatigueGastrointestinal discomfortHeadachesMenstrual cycle irregularitiesMood alteredMyalgiaNauseaPelvic painVomitingheadache (self-limited)abdominal pain

Drug interactions

Berotralstat
Severe
Database

Drug interaction classified as: absorption

Source: DDInter

Colchicine
Severe
Database

Drug interaction classified as: excretion

Source: DDInter

Edoxaban
Severe
Database

Clinical effect not specified

Source: DDInter

Venetoclax
Severe
Database

Clinical effect not specified

Source: DDInter

8 additional low-confidence interactions hidden — those rows lack a documented mechanism or management plan in our sources.

Related guidelines

Other Progestogen drugs

Ask House about Ulipristal Acetate

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Sources: Goodman & Gilman 14e, BNF·Verified: 2026-05-10 · House clinical team