Amiodarone
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Drug reference
Eslicarbazepine
Antiepileptic
Also known as Eslicarbazepine acetate, Aptiom
Antiepileptic
CDSCO approvedSchedule H
EXCRETION
—
not curated
INTERACTIONS
12 major
SEVERE in our sources
PREGNANCY
Women of child-bearing potential should discuss with a
FDA category + note
Top interactionssee all 12 →
- AmiodaroneSevereDatabaseDDInter
- BedaquilineSevereDatabaseDDInter
- BenzhydrocodoneSevereDatabaseDDInter
- BrigatinibSevereDatabaseDDInter
Mechanism
Eslicarbazepine acts by targeting voltage-gated sodium channels (Nav). This action helps to modulate neuronal excitability, which is characteristic of antiepileptic drugs.
Indications
Epilepsy
Dosing
- Adult
- Monotherapy: initially 400 mg OD for 1-2 weeks, then 800 mg OD, increase if needed to 1.2 g OD (max 1.6 g). Adjunctive: initially 400 mg OD for 1-2 weeks, then 800 mg OD (max 1.2 g).
- Max dose
- 1.6 g/day (monotherapy); 1.2 g/day (adjunctive)
Side effects
Serious
- Antiepileptic hypersensitivity syndrome
Pregnancy & lactation
Pregnancy
Women of child-bearing potential should discuss with a
Drug interactions
Bedaquiline
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Benzhydrocodone
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Brigatinib
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Buprenorphine
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Butorphanol
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Capmatinib
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Cobimetinib
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Dienogest
Severe
Database
Clinical effect not specified
Source: DDInter
Doravirine
Severe
Database
Clinical effect not specified
Source: DDInter
Drospirenone
Severe
Database
Clinical effect not specified
Source: DDInter
Erdafitinib
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Related guidelines
Initial monotherapy for newly diagnosed epilepsy
IAN · Neurology · 2023
Initial monotherapy for newly diagnosed epilepsy
ILAE · Neurology · 2013
Status epilepticus
AAN · Neurology · 2020
Functional (psychogenic non-epileptic) seizures
AAN · Neurology · 2026
Painful diabetic peripheral neuropathy
AAN · Neurology · 2022
Other Antiepileptic drugs
Ask House about Eslicarbazepine
Continue into a citation-backed clinical answer with the drug context already attached.
Sources: BNF·Verified: 2026-05-10 · House clinical team